Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901042 | 0.80 | PDGFRB (0.59) | EGFRPDGFRBPDGFRAFGFR2 | |
| SCHEMBL5012780 | 0.68 | CYP1A2 (0.47) | PDGFRBPDGFRAKDM4EALDH1A1MEN1 | |
| SCHEMBL38652754 | 0.68 | ACP1 (0.39) | SMN1; SMN2KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL3907849 | 0.66 | PDGFRB (0.61) | EGFRPDGFRBPDGFRAFGFR2 | |
| SCHEMBL22188227 | 0.66 | PDGFRA (0.45) | EGFRPDGFRBPDGFRAFGFR2 | |
| SCHEMBL7157491 | 0.66 | PDGFRB (0.60) | PDGFRBPDGFRASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7484470 | 0.66 | PDGFRA (0.74) | EGFRPDGFRBPDGFRAFGFR2 | |
| SCHEMBL3900264 | 0.64 | EGFR (0.74) | EGFRPDGFRBPDGFRAFGFR2 | |
| SCHEMBL3907506 | 0.64 | PDGFRB (0.71) | EGFRPDGFRBPDGFRAFGFR2 | |
| SCHEMBL4745598 | 0.64 | PDPK1 (0.75) | SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |