Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 7/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.48 |
| ▸ | GAK | O14976 | 4/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377512 | 0.79 | PIK3CD (0.73) | PDGFRBPDGFRAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL23651405 | 0.75 | NPC1 (0.46) | PDGFRBPDGFRAPIK3CDPIK3CAMTOR | |
| SCHEMBL31060782 | 0.75 | PDGFRB (1.00) | PDGFRBPDGFRA | |
| SCHEMBL19705335 | 0.74 | NPC1 (0.58) | PDGFRBPDGFRAPIK3CDPIK3CAPIK3CG | |
| SCHEMBL7159656 | 0.73 | PDGFRB (0.68) | PDGFRBPDGFRAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL14019133 | 0.73 | CYP19A1 (0.48) | PDGFRBPDGFRAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL5012780 | 0.73 | CYP1A2 (0.47) | PDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL14438060 | 0.73 | PDGFRB (0.58) | PDGFRBPDGFRADYRK1ADYRK1BGAK | |
| SCHEMBL28800392 | 0.72 | NPC1 (0.70) | PDGFRBPDGFRANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18774825 | 0.72 | MAOB (0.51) | PDGFRBPDGFRANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030004165-A1 | Polyazanaphthalene compounds and pharmaceutical use thereof | AJINOMOTO CO. INC (JP) | 2003-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004165-A1 | Polyazanaphthalene compounds and pharmaceutical use thereof | MMP1, TNF, MMP12 | PDGFRB 663/4885PDGFRA 1117/4885PIK3CD 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.