Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3296184 | 0.83 | BCHE (0.44) | DRD2CYP2D6BCHESIGMAR1HTR1A | |
| SCHEMBL5232481 | 0.74 | PTGER2 (0.39) | — | |
| SCHEMBL6758153 | 0.73 | BCHE (0.59) | DRD2BCHESIGMAR1 | |
| SCHEMBL27515867 | 0.72 | BCHE (0.58) | DRD2CYP2D6BCHESIGMAR1 | |
| SCHEMBL28989835 | 0.72 | BCHE (0.58) | DRD2CYP2D6BCHESIGMAR1 | |
| SCHEMBL28256253 | 0.72 | BCHE (0.58) | DRD2CYP2D6BCHESIGMAR1 | |
| SCHEMBL28989836 | 0.72 | BCHE (0.58) | DRD2CYP2D6BCHESIGMAR1 | |
| SCHEMBL19259383 | 0.72 | BCHE (0.58) | DRD2CYP2D6BCHESIGMAR1 | |
| SCHEMBL9571237 | 0.72 | BCHE (0.58) | DRD2CYP2D6BCHESIGMAR1 | |
| SCHEMBL9861039 | 0.71 | MEN1 (0.43) | DRD2CYP2D6BCHESIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |