Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104678 | 0.85 | KMT2A (0.46) | KMT2AMAPK1L3MBTL1MEN1TDP1 | |
| SCHEMBL19040901 | 0.79 | KMT2A (0.41) | KMT2AMAPK1L3MBTL1MEN1TDP1 | |
| SCHEMBL22023973 | 0.76 | KMT2A (0.40) | KMT2AMAPK1L3MBTL1MEN1TDP1 | |
| SCHEMBL23597829 | 0.74 | ALDH1A1 (0.39) | KMT2AMAPK1L3MBTL1MEN1TDP1 | |
| SCHEMBL23874215 | 0.73 | KMT2A (0.37) | KMT2AMAPK1L3MBTL1MEN1TDP1 | |
| SCHEMBL21236222 | 0.71 | ALDH1A1 (0.36) | KMT2AMAPK1L3MBTL1MEN1TDP1 | |
| SCHEMBL762439 | 0.70 | KMT2A (0.65) | KMT2AMAPK1L3MBTL1MEN1TDP1 | |
| SCHEMBL13836119 | 0.70 | KMT2A (0.46) | KMT2AMAPK1L3MBTL1MEN1TDP1 | |
| SCHEMBL1820230 | 0.70 | KMT2A (0.46) | KMT2AMAPK1L3MBTL1MEN1TDP1 | |
| SCHEMBL21577670 | 0.70 | KMT2A (0.35) | KMT2AMAPK1L3MBTL1MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |