Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 2/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093626 | 0.80 | TRPM8 (0.48) | ADH1AADH1CTRPM8MEN1KMT2A | |
| SCHEMBL2091298 | 0.78 | TRPM8 (0.49) | ADH1AADH1CTRPM8MEN1KMT2A | |
| SCHEMBL27206868 | 0.74 | HTR2A (0.46) | ADH1AADH1CL3MBTL1MEN1KMT2A | |
| SCHEMBL6002977 | 0.71 | KMT2A (0.48) | ADH1AADH1CL3MBTL1MEN1KMT2A | |
| SCHEMBL6003174 | 0.71 | TRPM8 (0.43) | TRPM8L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL27206290 | 0.71 | HTR2A (0.44) | ADH1AADH1CL3MBTL1MEN1KMT2A | |
| SCHEMBL3149066 | 0.71 | HTR2A (0.47) | ADH1AADH1CL3MBTL1MEN1KMT2A | |
| SCHEMBL8171737 | 0.71 | TRPM8 (0.49) | ADH1AADH1CTRPM8MEN1KMT2A | |
| SCHEMBL5545663 | 0.71 | TRPM8 (0.56) | ADH1AADH1CTRPM8MEN1KMT2A | |
| SCHEMBL5545662 | 0.71 | TRPM8 (0.56) | ADH1AADH1CTRPM8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |