Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 7/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222469 | 0.83 | NOTUM (0.53) | KDM1AHDAC1HDAC8HDAC6NOTUM | |
| SCHEMBL30413026 | 0.83 | NOTUM (0.53) | KDM1AHDAC1HDAC8HDAC6NOTUM | |
| Hydrochloric Acid SCHEMBL25232027 | 0.82 | NOTUM (0.52) | KDM1AHDAC1HDAC8HDAC6NOTUM | |
| SCHEMBL17807352 | 0.82 | KDM1A (0.43) | CYP11B2KDM1ANR1H2NOTUMGPR119 | |
| SCHEMBL5599315 | 0.80 | DPP4 (0.37) | KDM1AHDAC1HDAC8HDAC6NOTUM | |
| SCHEMBL5599635 | 0.79 | HDAC1 (0.38) | KDM1AHDAC1HDAC8HDAC6NOTUM | |
| SCHEMBL1223344 | 0.78 | NOTUM (0.41) | KDM1AHDAC1HDAC8HDAC6NOTUM | |
| SCHEMBL20955744 | 0.77 | NOTUM (0.57) | KDM1AHDAC1HDAC8HDAC6NOTUM | |
| SCHEMBL6002678 | 0.77 | KCNH2 (0.43) | KDM1AHDAC1HDAC8HDAC6NOTUM | |
| SCHEMBL1195029 | 0.77 | AKT1 (0.41) | KDM1AHDAC1HDAC8HDAC6NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694677-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | Syngenta Participations AG (CH) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005061500-A1 | SPIROPIPERIDINE DERIVATIVES FOR CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-07 | — | — | WO | disclosed |