Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAOA | P21397 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | NQO1 | P15559 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22960257 | 0.76 | CHRM2 (0.53) | ALDH1A1KDM4EMAOAMAPTHPGD | |
| SCHEMBL2442045 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4EMAOAMAPTHPGD | |
| SCHEMBL31450995 | 0.73 | AHR (0.45) | ALDH1A1KDM4EMAOAMAPTHPGD | |
| SCHEMBL4741002 | 0.73 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EMAOAMAPTHPGD | |
| SCHEMBL15442574 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EMAOAMAPTHPGD | |
| SCHEMBL11389406 | 0.73 | KDM4E (0.43) | ALDH1A1KDM4EMAOAMAPTHPGD | |
| SCHEMBL2675092 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAOAMAPTHPGD | |
| SCHEMBL22273765 | 0.73 | KDM4E (0.47) | ALDH1A1KDM4EMAOAMAPTHPGD | |
| SCHEMBL31318453 | 0.73 | CYP2C19 (0.46) | ALDH1A1KDM4EMAOAMAPTHPGD | |
| SCHEMBL3380593 | 0.73 | CYP2C19 (0.46) | ALDH1A1KDM4EMAOAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |