Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 5/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EPM2A | O95278 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2609996 | 0.84 | HTR1B (0.41) | HTR1BCYP2A6KDM4ECYP3A4CYP2D6 | |
| SCHEMBL27097447 | 0.81 | HTR1B (0.41) | HTR1BCYP2A6KDM4ECYP3A4CYP2D6 | |
| SCHEMBL13713915 | 0.77 | ESR1 (0.44) | HTR1BCYP2A6KDM4ECYP3A4CYP2D6 | |
| SCHEMBL20858618 | 0.76 | EPM2A (0.45) | HTR1BCYP2A6KDM4ECYP3A4CYP2D6 | |
| SCHEMBL15582382 | 0.75 | EPM2A (0.42) | HTR1BCYP2A6KDM4ECYP3A4CYP2D6 | |
| SCHEMBL6090212 | 0.73 | HTR1B (0.41) | HTR1BCYP2A6KDM4ECYP3A4CYP2D6 | |
| SCHEMBL24111657 | 0.73 | HTR1B (0.50) | HTR1BCYP2A6KDM4ECYP3A4CYP2D6 | |
| SCHEMBL25483158 | 0.72 | HTR1B (0.42) | HTR1BCYP2A6KDM4ECYP3A4CYP2D6 | |
| SCHEMBL24111653 | 0.71 | HTR1B (0.48) | HTR1BCYP2A6KDM4ECYP3A4CYP2D6 | |
| SCHEMBL15590665 | 0.70 | EPM2A (0.44) | HTR1BCYP2A6KDM4ECYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |