Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.46 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5368532 | 0.99 | TACR1 (0.45) | TACR1RHOCRHOAOPRD1 | |
| Hydrochloric Acid SCHEMBL5366247 | 0.88 | TACR1 (0.42) | TACR1RHOCRHOA | |
| Hydrochloric Acid SCHEMBL5369016 | 0.86 | TACR1 (0.47) | TACR1RHOCRHOA | |
| SCHEMBL5360994 | 0.82 | TACR1 (0.53) | TACR1RHOCRHOA | |
| Hydrochloric Acid SCHEMBL5366661 | 0.81 | TACR1 (0.50) | TACR1 | |
| Hydrochloric Acid SCHEMBL5360103 | 0.81 | TACR1 (0.52) | TACR1RHOCRHOA | |
| SCHEMBL6003097 | 0.81 | TACR1 (0.48) | TACR1RHOCRHOA | |
| SCHEMBL6003101 | 0.81 | TACR1 (0.48) | TACR1RHOCRHOA | |
| Hydrochloric Acid SCHEMBL5368530 | 0.80 | TACR1 (0.48) | TACR1RHOCRHOA | |
| Hydrochloric Acid SCHEMBL5368523 | 0.80 | TACR1 (0.48) | TACR1RHOCRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140924-B1 | PIPERAZINE DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2006-03-22 | — | — | EP | disclosed |