SCHEMBL6003128

SCHEMBL6003128

Cc1cc(C(=S)N2CCN(CCN3C[C@@H](C)O[C@@H](C)C3)C[C@H]2Cc2ccc(Cl)c(C(C)(C)C)c2O[SiH](C)C)cc(C(F)(F)F)c1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 20/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5425448 0.84 TACR1 (0.33) TACR1
SCHEMBL6003130 0.78 TACR1 (0.32) TACR1
SCHEMBL6003132 0.78 TACR1 (0.32) TACR1
SCHEMBL6003138 0.76 TSHR (0.31)
Hydrochloric Acid SCHEMBL7863825 0.70 RHOC (0.42) TACR1
Hydrochloric Acid SCHEMBL5363711 0.70 RHOC (0.42) TACR1
Hydrochloric Acid SCHEMBL5363706 0.70 RHOC (0.42) TACR1
Hydrochloric Acid SCHEMBL5369560 0.69 TACR1 (0.42) TACR1
SCHEMBL5379459 0.66 TACR1 (0.43) TACR1
SCHEMBL5379463 0.66 TACR1 (0.43) TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140924-B1 PIPERAZINE DERIVATIVES ASTELLAS PHARMA INC (JP) 2006-03-22 EP disclosed