Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14354479 | 0.86 | MEN1 (0.38) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL28559339 | 0.84 | MEN1 (0.44) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL283884 | 0.84 | MEN1 (0.46) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL13755066 | 0.83 | MEN1 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL354404 | 0.82 | CYP4F2 (0.36) | MEN1KMT2AL3MBTL1CYP4F2CYP4A11 | |
| SCHEMBL15074624 | 0.81 | MEN1 (0.42) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL21359810 | 0.81 | MEN1 (0.42) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL9478485 | 0.81 | MEN1 (0.42) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL3519692 | 0.80 | MEN1 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL28563052 | 0.80 | MEN1 (0.46) | MEN1KMT2AL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859610-B1 | IBOGAMINE CONGENERS | ALBANY MEDICAL COLLEGE (US) | 2006-01-11 | — | — | EP | disclosed |
| EP-0859610-A4 | IBOGAMINE CONGENERS | ALBANY MEDICAL COLLEGE (US) | 2002-05-15 | — | — | EP | disclosed |
| US-6211360-B1 | DRUG ABRUSE THERAPY; PLANT EXTRACTS | ALBANY MEDICAL COLLEGE | 2001-04-03 | — | — | US | disclosed |
| EP-0859610-A1 | IBOGAMINE CONGENERS | ALBANY MEDICAL COLLEGE (US) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997005869-A1 | IBOGAMINE CONGENERS | ALBANY MEDICAL COLLEGE (US) | 1997-02-20 | — | — | WO | disclosed |