Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2091566 | 0.83 | SLC6A3 (0.45) | SLC6A3DRD2SLC6A2GRIN2BGRIN1 | |
| SCHEMBL2094057 | 0.83 | GRIN2B (0.40) | SLC6A3DRD2SLC6A2GRIN2BGRIN1 | |
| SCHEMBL2090839 | 0.82 | SLC6A3 (0.47) | SLC6A3DRD2SLC6A2GRIN2BGRIN1 | |
| SCHEMBL2091568 | 0.81 | SLC6A3 (0.49) | SLC6A3DRD2SLC6A2GRIN2BGRIN1 | |
| SCHEMBL17288587 | 0.79 | SLC6A3 (0.45) | SLC6A3DRD2SLC6A2GRIN2BGRIN1 | |
| SCHEMBL1047281 | 0.78 | GRIN2B (0.43) | SLC6A3DRD2SLC6A2GRIN2BGRIN1 | |
| SCHEMBL2097493 | 0.75 | SLC6A3 (0.42) | SLC6A3DRD2SLC6A2GRIN2BGRIN1 | |
| SCHEMBL2097495 | 0.75 | SLC6A3 (0.42) | SLC6A3DRD2SLC6A2GRIN2BGRIN1 | |
| SCHEMBL23881813 | 0.75 | SLC6A3 (0.48) | SLC6A3DRD2SLC6A2GRIN2BGRIN1 | |
| SCHEMBL2094830 | 0.75 | SLC6A3 (0.47) | SLC6A3DRD2SLC6A2GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |