SCHEMBL6003230

SCHEMBL6003230

O=C(O)c1c(F)c(F)c(C(=O)O)c2c(C(=O)O)c(F)c(F)c(C(=O)O)c12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP1A2 P05177 2/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
GAA P10253 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ASPH Q12797 1/20 0.34
KDM8 Q8N371 1/20 0.34
HTT P42858 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA12 O43570 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7717691 0.88 CES2 (0.39) MEN1KMT2ASMN1; SMN2CYP1A2CRHBP
SCHEMBL141037 0.86 CYP1A2 (0.40) MEN1KMT2ASMN1; SMN2CYP1A2CRHBP
SCHEMBL3202669 0.85 MEN1 (0.37) MEN1KMT2ASMN1; SMN2CYP1A2CRHBP
SCHEMBL3368718 0.83 MEN1 (0.36) MEN1KMT2ASMN1; SMN2CYP1A2CRHBP
SCHEMBL336394 0.83 CES2 (0.43) MEN1KMT2ASMN1; SMN2CYP1A2CRHBP
Fluoride SCHEMBL2393600 0.83 CYP1A2 (0.38) MEN1KMT2ASMN1; SMN2CYP1A2CRHBP
Hydrochloric Acid SCHEMBL4414501 0.83 CYP1A2 (0.38) MEN1KMT2ASMN1; SMN2CYP1A2CRHBP
Hydrochloric Acid SCHEMBL7881715 0.83 CYP1A2 (0.38) MEN1KMT2ASMN1; SMN2CYP1A2CRHBP
SCHEMBL29191767 0.83 CYP1A2 (0.38) MEN1KMT2ASMN1; SMN2CYP1A2CRHBP
SCHEMBL203915 0.83 CES2 (0.43) MEN1KMT2ASMN1; SMN2CYP1A2CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7092608-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-15 US disclosed
US-7082244-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-25 US disclosed
US-20060159413-A1 POLYIMIDE OPTICAL MATERIALS, POLYIMIDE PRECURSOR SOLUTIONS AND OPTICAL WAVEGUIDE ELEMENTS KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-20 US disclosed
US-20040197064-A1 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2004-10-07 US disclosed
US-6051722-A PRECURSOR FOR POLYIMIDE COPOLYMER; USABLE IN OPTICAL LONG-DISTANCE COMMUNICATION, SIGNAL PROCESSING, PHOTOELECTRIC HYBRID CIRCUITS AND OPTICAL COMPUTERS HITACHI CHEMICAL COMPANY, LTD. (JP) 2000-04-18 US disclosed
US-5834575-A POLYIMIDE OR POLYACRYLATE WITH PENDANT GROUP CONTAINING THIOPHENE RING, BENZENE RING AND VICINAL NITRILE GROUPS, SWITCHES FOR OPTICAL SIGNALS, COMMUNICATION TECHNOLOGY HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-11-10 US disclosed