Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 8/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586102 | 0.85 | PKM (0.72) | PKMMAPTRAB9ANPC1GAA | |
| SCHEMBL10816504 | 0.84 | PKM (1.00) | PKMMAPTRAB9ANPC1GAA | |
| SCHEMBL20852455 | 0.81 | PKM (0.71) | PKMMAPTRAB9ANPC1GAA | |
| SCHEMBL13658035 | 0.80 | PKM (0.69) | PKMMAPTRAB9ANPC1GAA | |
| SCHEMBL13134186 | 0.80 | PKM (0.64) | PKMMAPTRAB9ANPC1GAA | |
| SCHEMBL13134187 | 0.78 | PKM (0.71) | PKMMAPTRAB9ANPC1GAA | |
| SCHEMBL10984551 | 0.77 | PKM (0.57) | PKMMAPTRAB9ANPC1GAA | |
| SCHEMBL7405156 | 0.77 | MAPT (0.45) | PKMMAPTRAB9ANPC1GAA | |
| SCHEMBL22246652 | 0.76 | PKM (0.58) | PKMMAPTRAB9ANPC1GAA | |
| SCHEMBL17101667 | 0.76 | PKM (0.63) | PKMMAPTRAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1353926-B1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | SOD CONSEILS RECH APPLIC (FR) | 2006-03-08 | — | — | EP | claimed |
| JP-2004533456-A | — | — | 2004-11-04 | — | — | JP | claimed |
| EP-1438039-A2 | PRODUCT COMPRISING MIKANOLIDE, DIHYDROMIKANOLIDE OR AN ANALOGUE THEREOF COMBINED WITH ANOTHER ANTI-CANCER AGENT FOR THERAPEUTIC USE IN CANCER TREATMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-07-21 | — | — | EP | claimed |
| EP-1353926-A1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2003-10-22 | — | — | EP | claimed |
| WO-2002096348-A2 | PRODUCT COMPRISING MIKANOLIDE, DIHYDROMIKANOLIDE OR AN ANALOGUE THEREOF COMBINED WITH ANOTHER ANTI-CANCER AGENT FOR THERAPEUTIC USE IN CANCER TREATMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-12-05 | — | — | WO | claimed |
| WO-2002055523-A1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-07-18 | — | — | WO | claimed |
| EP-1353926-B1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | SOD CONSEILS RECH APPLIC (FR) | 2006-03-08 | — | — | EP | disclosed |
| EP-1438039-A2 | PRODUCT COMPRISING MIKANOLIDE, DIHYDROMIKANOLIDE OR AN ANALOGUE THEREOF COMBINED WITH ANOTHER ANTI-CANCER AGENT FOR THERAPEUTIC USE IN CANCER TREATMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-07-21 | — | — | EP | disclosed |
| EP-1353926-A1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002096348-A2 | PRODUCT COMPRISING MIKANOLIDE, DIHYDROMIKANOLIDE OR AN ANALOGUE THEREOF COMBINED WITH ANOTHER ANTI-CANCER AGENT FOR THERAPEUTIC USE IN CANCER TREATMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-12-05 | — | — | WO | disclosed |
| WO-2002055523-A1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-07-18 | — | — | WO | disclosed |