SCHEMBL6003274

SCHEMBL6003274

c1cc(-c2cccc(-c3cccc4c3oc3ccccc34)c2)cc(-c2ccc3c(ccc4ccccc43)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.58
GGPS1 O95749 1/20 0.46
PRKDC P78527 6/20 0.46
PTGES2 Q9H7Z7 1/20 0.43
PLA2G2A P14555 2/20 0.40
PLA2G4A P47712 2/20 0.40
CYP1B1 Q16678 4/20 0.38
CYP1A1 P04798 3/20 0.38
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38
PLA2G10 O15496 1/20 0.37
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 3/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 2/20 0.37
TSHR P16473 2/20 0.37
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17167456 0.96 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2CYP1B1
SCHEMBL25118635 0.96 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2CYP1B1
SCHEMBL17268977 0.93 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2CYP1B1
SCHEMBL18086153 0.93 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL16303010 0.93 ALOX5 (0.66) ALOX5GGPS1PRKDCPTGES2CYP1B1
SCHEMBL18086152 0.92 ALOX5 (0.61) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL18996053 0.90 ALOX5 (0.53) ALOX5GGPS1PRKDCPTGES2PLA2G2A
SCHEMBL15856959 0.90 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2CYP1B1
SCHEMBL13706102 0.89 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2CYP1B1
SCHEMBL12768027 0.89 ALOX5 (0.56) ALOX5GGPS1PRKDCPTGES2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729541-B2 Phenanthrene compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2014-05-20 US disclosed
US-8729541-B2 Phenanthrene compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2014-05-20 US disclosed
US-20130207096-A1 PHENANTHRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-15 US disclosed
US-20130207096-A1 PHENANTHRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-15 US disclosed
WO-2012060307-A1 PHENANTHRENE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-05-10 WO disclosed