Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23267860 | 0.83 | HPGD (0.48) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL26098762 | 0.78 | GPR119 (0.53) | HPGDGPR119RECQLEPHX1 | |
| SCHEMBL26100517 | 0.78 | GPR119 (0.53) | HPGDGPR119RECQLEPHX1 | |
| SCHEMBL26099289 | 0.78 | GPR119 (0.53) | HPGDGPR119RECQLEPHX1 | |
| SCHEMBL19633473 | 0.77 | HPGD (0.54) | HPGDGPR119RECQLEPHX1 | |
| SCHEMBL30750542 | 0.77 | GPR119 (0.50) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL4048084 | 0.76 | MEN1 (0.41) | HPGDGPR119MEN1KMT2ARECQL | |
| SCHEMBL4047915 | 0.76 | MEN1 (0.41) | HPGDGPR119MEN1KMT2ARECQL | |
| SCHEMBL118561 | 0.76 | GPR119 (0.57) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL4711418 | 0.76 | HPGD (0.55) | HPGDGPR119MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1723150-A1 | RIFAMYCIN IMINO DERIVATIVES EFFECTIVE AGAINST DRUG-RESISTANT MICROBES | Cumbre Pharmaceuticals Inc. (US) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005070941-A1 | RIFAMYCIN IMINO DERIVATIVES EFFECTIVE AGAINST DRUG-RESISTANT MICROBES | CUMBRE PHARMACEUTICALS INC. (US) | 2005-08-04 | — | — | WO | disclosed |