2-Pyrrolidone

2-Pyrrolidone

SCHEMBL6003660

O=C1CCCN1.OCCO

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.75
CRBN Q96SW2 4/20 0.64
FKBP5 Q13451 1/20 0.64
KDM4E B2RXH2 2/20 0.44
GAA P10253 2/20 0.44
POLB P06746 1/20 0.44
MERTK Q12866 1/20 0.33
KMT2A Q03164 2/20 0.32
PARP1 P09874 3/20 0.31
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Pyrrolidone SCHEMBL9303170 1.00 OR51E2 (0.75) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL27512532 1.00 OR51E2 (0.75) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL9016114 0.98 OR51E2 (0.71) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL4661034 0.95 OR51E2 (0.68) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL28324136 0.91 OR51E2 (0.68) OR51E2CRBNFKBP5KDM4EGAA
Caprolactam SCHEMBL2345807 0.91 CRBN (0.73) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL8973092 0.89 OR51E2 (0.65) OR51E2CRBNFKBP5KDM4EGAA
1,6-Hexanediol SCHEMBL7071741 0.89 OR51E2 (0.65) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL28327039 0.89 OR51E2 (0.65) OR51E2CRBNFKBP5KDM4EGAA
2-Pyrrolidone SCHEMBL5051625 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109493994-B Critical superconducting silver paste based on linear silver nanoparticles and preparation method thereof 广东银研高新材料股份有限公司 2021-06-18 CN claimed
CN-108376573-B A method of high shielding effect flexibility form film is prepared using nano-silver thread 西南科技大学 2019-12-03 CN claimed
CN-109604633-A A kind of preparation method of nano-silver thread 广东银研高新材料股份有限公司 2019-04-12 CN claimed
CN-109493994-A Critical superconduction silver paste based on linear silver nano-grain and preparation method thereof 广东银研高新材料股份有限公司 2019-03-19 CN claimed
CN-108927529-A A kind of preparation method of silver nanoparticle ring 深圳市华科创智技术有限公司 2018-12-04 CN claimed
CN-108376573-A A method of preparing high shielding effect flexibility form film using nano-silver thread 西南科技大学 2018-08-07 CN claimed
CN-105602201-A Preparation method of high-strength conductive polymer nanocomposite UNIV SOUTHWEST SCIENCE & TECH 2016-05-25 CN claimed
CN-103183357-B The modified with noble metals method of HTS SINOPEC CORP. (CN) 2016-03-02 CN claimed
CN-103420869-A Method of ammoxidation of cyclohexane CHINA PETROLEUM & CHEMICAL 2013-12-04 CN claimed
CN-103183357-A Precious metal modification method of titanium silicon molecular sieve CHINA PETROLEUM & CHEMICAL 2013-07-03 CN claimed
CN-101537372-B Modification method for titanium-silicon molecular sieve SINOPEC CORP. (CN) 2011-12-21 CN claimed
CN-102079695-A Method for catalytically oxidizing cyclohexane CHINA PETROLEUM & CHEMICAL 2011-06-01 CN claimed
CN-102079694-A Preparation method of cyclohexanone from oxidation of cyclohexanol CHINA PETROLEUM & CHEMICAL 2011-06-01 CN claimed
CN-101618339-B Method for modifying titanium-silicon molecular sieve RES INST CN PETROCHEMICAL CORP 2011-02-09 CN claimed
CN-101618339-A Method for modifying titanium-silicon molecular sieve CHINA PETROLEUM & CHEMICAL 2010-01-06 CN claimed
CN-101618338-A Method for modifying titanium-silicon molecular sieve CHINA PETROLEUM & CHEMICAL 2010-01-06 CN claimed
CN-101537372-A Modification method for titanium-silicon molecular sieve CHINA PETROCHEMICAL CORP 2009-09-23 CN claimed
CN-101537371-A Modification method for titanium-silicon molecular sieve CHINA PETROCHEMICAL CORP 2009-09-23 CN claimed
CN-117185977-A Preparation method of amisulpride intermediate 江苏阿尔法药业股份有限公司 2023-12-08 CN disclosed
US-6072086-A QUENCHING AQUEOUS FORMALDEHYDE SOLUTION WITH COMPOSITION COMPRISING FIRST AGENT CAPABLE OF REACTING WITH FORMALDEHYDE, SECOND AGENT CAPABLE OF SUBSTANTIALLY PREVENTING FIRST AGENT FROM REACTING WITH FORMALDEHYDE FOR FINITE TIME PERIOD INTERGEN COMPANY (US) 2000-06-06 US disclosed