Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72899 | 0.87 | MRGPRX4 (0.57) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL644216 | 0.85 | SMN1; SMN2 (0.58) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL31442462 | 0.85 | SMN1; SMN2 (0.58) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27439509 | 0.83 | MRGPRX4 (0.59) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27657867 | 0.83 | LOXL2 (0.61) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27801100 | 0.83 | MRGPRX4 (0.56) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3069825 | 0.83 | MRGPRX4 (0.56) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27800201 | 0.83 | MRGPRX4 (0.56) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27956214 | 0.83 | MRGPRX4 (0.56) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7045225 | 0.83 | MAOB (0.64) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |