SCHEMBL6004091

SCHEMBL6004091

BrCCCCCc1c2nc(cc3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.41
▸ STAT1 P42224 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7647119 0.87 STAT3 (0.41) STAT3STAT1
SCHEMBL6003904 0.87 STAT3 (0.41) STAT3STAT1
SCHEMBL3520094 0.87 STAT3 (0.41) STAT3STAT1
SCHEMBL3522373 0.87 STAT3 (0.41) STAT3STAT1
SCHEMBL15510967 0.87 STAT3 (0.41) STAT3STAT1
SCHEMBL7867113 0.87 STAT3 (0.41) STAT3STAT1
SCHEMBL5533945 0.86 STAT3 (0.49) STAT3STAT1
Hydrochloric Acid SCHEMBL27872840 0.86 STAT3 (0.40) STAT3STAT1
SCHEMBL5133634 0.86 STAT3 (0.42) STAT3STAT1
SCHEMBL17419215 0.84 STAT3 (0.43) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060293249-A1 Porphyrin derivatives PHOTOBIOTICS LIMITED 2006-12-28 — — US disclosed
EP-1562951-A2 PORPHYRIN DERIVATIVES Photobiotics Ltd. (GB) 2005-08-17 — — EP disclosed
WO-2004046151-A2 PORPHYRIN DERIVATIVES PHOTOBIOTICS LIMITED (GB) 2004-06-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060293249-A1 Porphyrin derivatives SLC2A3, SLC2A2, SCO2 STAT3 797/4885STAT1 1512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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