Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30369522 | 0.88 | CA12 (0.38) | HSP90AA1HSP90AB1ATRCA12CA1 | |
| SCHEMBL13247607 | 0.85 | CA12 (0.43) | HSP90AA1HSP90AB1ATRCA12CA1 | |
| SCHEMBL15677015 | 0.81 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1ATR | |
| SCHEMBL12225275 | 0.81 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1ATRCYP17A1 | |
| SCHEMBL3571997 | 0.81 | CA12 (0.41) | HSP90AA1HSP90AB1ATRCA12CA1 | |
| SCHEMBL1581324 | 0.80 | ATR (0.42) | ATRBRD9CYP17A1METAP1 | |
| SCHEMBL15584205 | 0.80 | ATR (0.42) | ATRCA12CA1CA9CA2 | |
| SCHEMBL29364468 | 0.80 | ATR (0.42) | ATRBRD9CYP17A1METAP1 | |
| SCHEMBL7416727 | 0.78 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1ATRCA12CA1 | |
| SCHEMBL30048786 | 0.78 | RXFP1 (0.43) | HSP90AA1HSP90AB1RXFP1BRD9METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060205751-A1 | Novel compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205751-A1 | Novel compounds | KCNN2, KCNN3, KCNN1 | HSP90AA1 4271/4885HSP90AB1 3974/4885ATR 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.