Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655163 | 0.81 | DHODH (0.41) | DHODHCDK5CDK5R1NPC1DHFR | |
| SCHEMBL361776 | 0.81 | AKT1 (0.49) | DHODHNPC1KMT2ALMNAMEN1 | |
| SCHEMBL28261532 | 0.79 | PDE10A (0.59) | DHODHNPC1KMT2ALMNAKDM4E | |
| SCHEMBL28185476 | 0.79 | ALDH1A1 (0.45) | DHODHCASP6NPC1KMT2ALMNA | |
| SCHEMBL28533234 | 0.79 | MAPK14 (0.45) | DHODHNPC1KMT2ALMNAMEN1 | |
| SCHEMBL1692394 | 0.79 | DHODH (0.44) | DHODHNPC1KMT2ALMNAKDM4E | |
| SCHEMBL9375622 | 0.76 | PARP1 (0.46) | DHODHKMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL9959092 | 0.76 | DHODH (0.40) | DHODHNPC1PIK3CGADORA2A | |
| SCHEMBL31520474 | 0.76 | FGFR1 (0.51) | NPC1DHFRKMT2AMEN1ADORA2A | |
| SCHEMBL28280374 | 0.76 | FGFR1 (0.51) | NPC1DHFRKMT2AMEN1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |