Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900929 | 0.88 | SRC (0.53) | SRCTGFBR1PDGFRBPDGFRAEGFR | |
| SCHEMBL3897482 | 0.87 | SRC (0.55) | SRCTGFBR1PDGFRBPDGFRAEGFR | |
| SCHEMBL3898480 | 0.84 | TGFBR1 (0.56) | SRCTGFBR1PDGFRBPDGFRA | |
| SCHEMBL3906131 | 0.84 | SRC (0.55) | SRCTGFBR1PDGFRBPDGFRAEGFR | |
| SCHEMBL13605214 | 0.83 | SRC (0.54) | SRCTGFBR1PDGFRBPDGFRAEGFR | |
| SCHEMBL3897825 | 0.83 | SRC (0.50) | SRCTGFBR1PDPK1PDGFRBPDGFRA | |
| SCHEMBL3901872 | 0.81 | SRC (0.51) | SRCTGFBR1PDGFRBPDGFRAEGFR | |
| SCHEMBL6004741 | 0.81 | SRC (0.46) | SRCTGFBR1PDGFRBPDGFRA | |
| SCHEMBL3894021 | 0.81 | SRC (0.53) | SRCTGFBR1PDGFRBPDGFRAEGFR | |
| SCHEMBL3905070 | 0.81 | PDGFRB (0.59) | SRCTGFBR1PDGFRBPDGFRAEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |