Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 11/20 | 0.52 |
| ▸ | SRC | P12931 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900624 | 0.96 | TGFBR1 (0.52) | TGFBR1SRCAXL | |
| SCHEMBL3898480 | 0.92 | TGFBR1 (0.56) | TGFBR1SRC | |
| SCHEMBL6004942 | 0.89 | TGFBR1 (0.55) | TGFBR1SRC | |
| SCHEMBL6004719 | 0.88 | TGFBR1 (0.52) | TGFBR1SRC | |
| SCHEMBL6004708 | 0.88 | TGFBR1 (0.52) | TGFBR1SRCMET | |
| SCHEMBL6004134 | 0.86 | KDM4E (0.52) | TGFBR1SRC | |
| SCHEMBL6004790 | 0.86 | TGFBR1 (0.47) | TGFBR1SRCMET | |
| SCHEMBL6004314 | 0.86 | TGFBR1 (0.52) | TGFBR1SRCAXL | |
| SCHEMBL6004880 | 0.86 | TGFBR1 (0.52) | TGFBR1SRCMET | |
| SCHEMBL3903240 | 0.85 | TGFBR1 (0.49) | TGFBR1SRCAXLMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |