Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29516649 | 0.83 | KMT2A (0.62) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL108993 | 0.83 | KMT2A (0.62) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL29392652 | 0.79 | GAA (0.67) | MAPTLMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL112411 | 0.79 | GAA (0.67) | MAPTLMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29393615 | 0.76 | KAT2B (0.68) | MAPTALDH1A1KMT2APKMGAA | |
| SCHEMBL125386 | 0.76 | KAT2B (0.68) | MAPTALDH1A1KMT2APKMGAA | |
| SCHEMBL5697339 | 0.75 | KMT2A (0.59) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9795841 | 0.75 | KMT2A (0.50) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9776320 | 0.75 | ALDH1A1 (0.53) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8992932 | 0.73 | ALDH1A1 (0.53) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006087195-A2 | DYE COMPOSITION COMPRISING AT LEAST ONE METHINE DYE OF PARTICULAR STRUCTURE AND PROCESS FOR IMPLEMENTATION THEREOF | L'OREAL (FR) | 2006-08-24 | — | — | WO | disclosed |