Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 18/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30905509 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| SCHEMBL30905503 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| SCHEMBL1890105 | 0.86 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| SCHEMBL22766451 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| SCHEMBL21200929 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| SCHEMBL6004820 | 0.85 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| SCHEMBL21200952 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| SCHEMBL30616279 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| SCHEMBL2174228 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 | |
| SCHEMBL27402291 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HSD17B10MAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |