SCHEMBL6005211

SCHEMBL6005211

O=C(O)C(F)(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 2/20 0.35
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8417596 0.84 THRB (0.62) THRBL3MBTL1
SCHEMBL5915219 0.84 THRB (0.62) THRBL3MBTL1
SCHEMBL28446928 0.84 THRB (0.62) THRBL3MBTL1
SCHEMBL8671924 0.84 THRB (0.62) THRBL3MBTL1
SCHEMBL8076744 0.84 THRB (0.62) THRBL3MBTL1
SCHEMBL11618473 0.83 THRB (0.71) THRBTSHRKDM4ETDP1USP2
SCHEMBL7647628 0.82 THRB (0.59) THRBL3MBTL1
SCHEMBL10421655 0.82 THRB (0.59) THRBL3MBTL1
SCHEMBL11538524 0.82 THRB (0.57) THRBTSHRL3MBTL1
SCHEMBL11536909 0.79 THRB (0.55) THRBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1686425-A1 METHOD FOR FORMING MULTILAYER RESIST Daikin Industries, Ltd. (JP) 2006-08-02 EP disclosed