SCHEMBL6005512

SCHEMBL6005512

CCOC(=O)c1sc(Cc2nc(C)c(C(=O)OCC)s2)nc1C

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.62
KDM4E B2RXH2 6/20 0.62
CDC7 O00311 1/20 0.61
DBF4 Q9UBU7 1/20 0.61
HPGD P15428 3/20 0.58
LMNA P02545 3/20 0.57
HSD17B10 Q99714 1/20 0.55
NPC1 O15118 2/20 0.52
MAPT P10636 5/20 0.51
RAB9A P51151 1/20 0.51
TSHR P16473 1/20 0.50
CYP1A2 P05177 1/20 0.50
NPSR1 Q6W5P4 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
DHODH Q02127 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5553648 0.89 ALDH1A1 (0.58) ALDH1A1KDM4ECDC7DBF4HPGD
SCHEMBL12034449 0.89 CDC7 (0.69) ALDH1A1KDM4ECDC7DBF4HPGD
SCHEMBL25094937 0.86 ALDH1A1 (0.55) ALDH1A1KDM4ECDC7DBF4HPGD
SCHEMBL11159741 0.86 ALDH1A1 (0.55) ALDH1A1KDM4ECDC7DBF4HPGD
SCHEMBL7610795 0.86 ALDH1A1 (0.55) ALDH1A1KDM4ECDC7DBF4HPGD
SCHEMBL14019450 0.85 CDC7 (0.61) ALDH1A1KDM4ECDC7DBF4HPGD
SCHEMBL3274867 0.85 ALDH1A1 (0.54) ALDH1A1KDM4ECDC7DBF4HPGD
SCHEMBL18792211 0.83 ALDH1A1 (0.52) ALDH1A1KDM4ECDC7DBF4HPGD
SCHEMBL14109854 0.83 RXFP1 (0.60) ALDH1A1KDM4ECDC7DBF4HPGD
SCHEMBL14109861 0.83 KDM4E (0.60) ALDH1A1KDM4ECDC7DBF4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1709039-A1 METALLIC COMPLEXES USED AS LIGHT-ABSORBENT COMPOUNDS IN THE INFORMATION LAYER OF OPTICAL DATA CARRIERS Lanxess Deutschland GmbH (DE) 2006-10-11 EP disclosed
WO-2005068459-A1 METALLIC COMPLEXES USED AS LIGHT-ABSORBENT COMPOUNDS IN THE INFORMATION LAYER OF OPTICAL DATA CARRIERS LANXESS DEUTSCHLAND GMBH (DE) 2005-07-28 WO disclosed