Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL6005530 | 1.00 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL16280460 | 0.90 | ALDH1A1 (0.70) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Salicylic Acid SCHEMBL8157144 | 0.87 | ALDH1A1 (0.75) | ALDH1A1ALOX15KDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL8157148 | 0.87 | ALDH1A1 (0.75) | ALDH1A1ALOX15KDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL28475198 | 0.87 | ALDH1A1 (0.75) | ALDH1A1ALOX15KDM4ECA12CA1 | |
| Phthalic Acid SCHEMBL5668586 | 0.84 | ALDH1A1 (1.00) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL1332278 | 0.84 | ALDH1A1 (1.00) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL10477086 | 0.84 | ALDH1A1 (1.00) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL146125 | 0.84 | ALDH1A1 (1.00) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL1686043 | 0.84 | ALDH1A1 (1.00) | ALDH1A1ALOX15AKR1C3KDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104237144-B | For adjusting, calibrating and/or checking the method and calibration insertion piece of the function of luminosity sensor | 恩德莱斯和豪瑟尔分析仪表两合公司 | 2018-12-07 | — | — | CN | disclosed |
| US-9322770-B2 | Method and calibration insert for adjusting, calibrating and/or checking a function of a photometric sensor | ENDRESS + HAUSER CONDUCTA GESELLSCHAFT FUR MESS- UND REGELTECHNIK MBH + CO. KG (DE) | 2016-04-26 | — | — | US | disclosed |
| CN-104237144-A | METHOD AND CALIBRATION INSERT FOR ADJUSTING, CALIBRATING AND/OR CHECKING A FUNCTION OF A PHOTOMETRIC SENSOR | CONDUCTA ENDRESS & HAUSER | 2014-12-24 | — | — | CN | disclosed |
| US-20140362381-A1 | METHOD AND CALIBRATION INSERT FOR ADJUSTING, CALIBRATING AND/OR CHECKING A FUNCTION OF A PHOTOMETRIC SENSOR | Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG (DE) | 2014-12-11 | — | — | US | disclosed |
| US-7071326-B2 | Anionic cellulose nitrate derivatives and aqueous dispersions thereof | WOLFF CELLULOSICS GMBH & CO. KG (DE) | 2006-07-04 | — | — | US | disclosed |
| US-20060117998-A1 | ANIONIC CELLULOSE NITRATE DERIVATIVES AND AQUEOUS DISPERSIONS THEREOF | WOLFF CELLULOSICS GMBH & CO. KG | 2006-06-08 | — | — | US | disclosed |
| US-5556835-A | CROSSLINKED ABSORBENT RESIN FOR ESSENTIAL OIL | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0631788-A1 | Gel-like fragrance composition | NIPPON SHOKUBAI CO., LTD. (JP) | 1995-01-04 | — | — | EP | disclosed |