Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | DAO | P14920 | 1/20 | 0.70 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.70 |
| ▸ | CES1 | P23141 | 5/20 | 0.58 |
| ▸ | CES2 | O00748 | 4/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL27540353 | 0.87 | TSHR (0.74) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL27807828 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL3173847 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL27392136 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28377937 | 0.85 | TSHR (0.70) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL3966600 | 0.84 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL407365 | 0.84 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL149318 | 0.84 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL975929 | 0.84 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2458489 | 0.84 | TSHR (1.00) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116376055-A | Photonic crystal gel with visual detection function and preparation method and application thereof | 武汉理工大学 | 2023-07-04 | — | — | CN | claimed |
| CN-116376055-A | Photonic crystal gel with visual detection function and preparation method and application thereof | 武汉理工大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-116376055-A | Photonic crystal gel with visual detection function and preparation method and application thereof | 武汉理工大学 | 2023-07-04 | — | — | CN | disclosed |
| EP-1386935-B1 | Dual stimuli-responsive hydrogels and their synthetic methods | KOREA INST SCI & TECH (KR) | 2006-01-25 | — | — | EP | disclosed |
| US-6784266-B2 | BLOCK POLYMERS HAVING BOTH THERMO- AND PH- RESPONSIVE PROPERTIES NECESSARY FOR DRUG DELIVERY SYSTEMS; COPOLYMERS BASED ON A SULFONAMIDE DERIVATIVE OF STYRENE (PH) AND N-ISOPROPYLACRYLAMIDE (HEAT); SULFA DRUGS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-08-31 | — | — | US | disclosed |
| US-20040024096-A1 | Dual stimuli-responsive hydrogels and their synthetic methods | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2004-02-05 | — | — | US | disclosed |
| EP-1386935-A1 | Dual stimuli-responsive hydrogels and their synthetic methods | Korea Institute of Science and Technology (KR) | 2004-02-04 | — | — | EP | disclosed |