Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005890 | 0.94 | CCR5 (0.80) | CCR5 | |
| SCHEMBL6008399 | 0.93 | CCR5 (0.79) | CCR5 | |
| SCHEMBL6008414 | 0.93 | CCR5 (0.81) | CCR5 | |
| SCHEMBL6008456 | 0.91 | CCR5 (0.81) | CCR5 | |
| SCHEMBL6008397 | 0.90 | CCR5 (0.75) | CCR5 | |
| SCHEMBL6008165 | 0.90 | CCR5 (0.78) | CCR5 | |
| SCHEMBL6009048 | 0.89 | CCR5 (0.79) | CCR5 | |
| SCHEMBL6009155 | 0.88 | CCR5 (0.82) | CCR5 | |
| SCHEMBL6009022 | 0.88 | CCR5 (0.77) | CCR5 | |
| SCHEMBL6007399 | 0.87 | CCR5 (0.75) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716156-A2 | CHEMOKINE CCR5 RECEPTOR MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-11-02 | — | — | EP | claimed |
| WO-2005075484-A2 | CHEMOKINE CCR5 RECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-18 | — | — | WO | claimed |