Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.85 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.85 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332678 | 1.00 | HTR3A (0.85) | HTR3ACHRNA7HRH3KCNH2CHRM4 | |
| SCHEMBL5332674 | 1.00 | HTR3A (0.85) | HTR3ACHRNA7HRH3KCNH2CHRM4 | |
| Hydrochloric Acid SCHEMBL6006772 | 0.99 | HTR3A (0.83) | HTR3ACHRNA7HRH3KCNH2CHRM4 | |
| SCHEMBL4699052 | 0.92 | HTR3A (1.00) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL5247514 | 0.80 | HTR3A (0.85) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL5247520 | 0.80 | HTR3A (0.85) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL5909648 | 0.80 | CHRNA7 (0.55) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL5909647 | 0.80 | CHRNA7 (0.55) | HTR3ACHRNA7KCNH2CHRM4CHRM5 | |
| SCHEMBL5251450 | 0.79 | HTR3A (0.58) | HTR3ACHRNA7HRH3KCNH2 | |
| SCHEMBL5251454 | 0.79 | HTR3A (0.58) | HTR3ACHRNA7HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006051410-A1 | AZABENZOXAZOLES FOR THE TREATMENT OF CNS DISORDERS | PFIZER INC. (US) | 2006-05-18 | — | — | WO | disclosed |