Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007960 | 1.00 | NAPRT (0.50) | NAPRTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL28624819 | 0.82 | NAPRT (0.52) | NAPRTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL14074321 | 0.80 | CYP1A2 (0.49) | NAPRTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL14523606 | 0.80 | CYP1A2 (0.49) | NAPRTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL7302432 | 0.75 | CYP1A2 (0.51) | NAPRTMEN1KMT2ACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9425932 | 0.73 | CYP3A4 (0.50) | NAPRTMEN1KMT2ACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10500949 | 0.73 | CYP3A4 (0.50) | NAPRTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL3844697 | 0.73 | NAPRT (0.52) | NAPRTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4764922 | 0.73 | NAPRT (0.52) | NAPRTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10592278 | 0.73 | GRM8 (0.48) | NAPRTKMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920345-A4 | IONTOPHORETIC DELIVERY OF CELL ADHESION INHIBITORS | VYTERIS INC (US) | 2006-05-10 | — | — | EP | disclosed |
| EP-0920345-A1 | IONTOPHORETIC DELIVERY OF CELL ADHESION INHIBITORS | Becton Dickinson and Company (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1997048443-A1 | IONTOPHORETIC DELIVERY OF CELL ADHESION INHIBITORS | BECTON DICKINSON AND COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |