Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005904 | 0.90 | CCR5 (0.62) | CCR5KCNH2 | |
| SCHEMBL6009138 | 0.90 | CCR5 (0.80) | CCR5KCNH2 | |
| SCHEMBL6008506 | 0.88 | CCR5 (0.79) | CCR5KCNH2 | |
| SCHEMBL6009111 | 0.87 | CCR5 (0.68) | CCR5KCNH2 | |
| SCHEMBL6008243 | 0.86 | CCR5 (0.73) | CCR5KCNH2 | |
| SCHEMBL6005859 | 0.85 | CCR5 (0.63) | CCR5KCNH2 | |
| SCHEMBL6008161 | 0.85 | CCR5 (0.85) | CCR5KCNH2 | |
| SCHEMBL4471153 | 0.83 | CCR5 (0.87) | CCR5KCNH2 | |
| SCHEMBL13604581 | 0.83 | CCR5 (0.87) | CCR5KCNH2 | |
| SCHEMBL6007371 | 0.83 | CCR5 (0.75) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716156-A2 | CHEMOKINE CCR5 RECEPTOR MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-11-02 | — | — | EP | claimed |
| WO-2005075484-A2 | CHEMOKINE CCR5 RECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-18 | — | — | WO | claimed |