Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458526 | 1.00 | CCR5 (1.00) | CCR5 | |
| SCHEMBL6008097 | 1.00 | CCR5 (1.00) | CCR5 | |
| SCHEMBL6007326 | 0.99 | CCR5 (1.00) | CCR5 | |
| SCHEMBL6006922 | 0.96 | CCR5 (0.93) | CCR5 | |
| SCHEMBL6005856 | 0.95 | CCR5 (0.91) | CCR5 | |
| SCHEMBL6008519 | 0.93 | CCR5 (0.88) | CCR5 | |
| SCHEMBL6006163 | 0.93 | CCR5 (0.88) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL6007096 | 0.93 | CCR5 (0.88) | CCR5 | |
| SCHEMBL6005984 | 0.93 | CCR5 (0.86) | CCR5 | |
| SCHEMBL6009071 | 0.92 | CCR5 (0.85) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716156-A2 | CHEMOKINE CCR5 RECEPTOR MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-11-02 | — | — | EP | claimed |
| WO-2005075484-A2 | CHEMOKINE CCR5 RECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-18 | — | — | WO | claimed |
| US-7332500-B2 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC | 2008-02-19 | — | — | US | disclosed |