Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6009773 | 0.91 | ABCB11 (0.58) | ABCB11TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL21297326 | 0.90 | ABCB11 (0.56) | ABCB11HTR2AHTR2CTUBB4ATUBB | |
| SCHEMBL9654895 | 0.89 | ABCB11 (0.47) | ABCB11HTR2AHTR2CTUBB4ATUBB | |
| SCHEMBL9654924 | 0.82 | ABCB11 (0.42) | ABCB11 | |
| SCHEMBL9657954 | 0.82 | ABCB11 (0.42) | ABCB11 | |
| SCHEMBL9641850 | 0.82 | ABCB11 (0.83) | ABCB11TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9642000 | 0.82 | ABCB11 (0.83) | ABCB11TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9657735 | 0.79 | TSHR (0.43) | ABCB11TDP1MAOB | |
| SCHEMBL9642189 | 0.79 | ABCB11 (0.59) | ABCB11TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9641621 | 0.79 | ABCB11 (0.59) | ABCB11TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242946-A | Treating herpes Viral infections | BIO-MEGA, INC. (CA) | 1993-09-07 | — | — | US | claimed |
| EP-0221474-B1 | PROCESS FOR THE MANUFACTURE OF 6-CHLORO-1,4-DIACETOXY-2,3-DIMETHOXYNAPHTHALENE | WARNER-LAMBERT COMPANY (US) | 1990-01-17 | — | — | EP | claimed |
| EP-0221474-A1 | Process for the manufacture of 6-chloro-1,4-diacetoxy-2,3-dimethoxynaphthalene | WARNER-LAMBERT COMPANY (US) | 1987-05-13 | — | — | EP | claimed |
| US-7132441-B2 | Immunosuppressive effects of administration of a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor | G.D. SEARLE & CO. (US) | 2006-11-07 | — | — | US | disclosed |
| US-5242946-A | Treating herpes Viral infections | BIO-MEGA, INC. (CA) | 1993-09-07 | — | — | US | disclosed |
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |