Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18635296 | 0.73 | CA1 (0.35) | — | |
| SCHEMBL10388008 | 0.70 | ALDH1A1 (0.47) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL2373498 | 0.70 | ALDH1A1 (0.47) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL5033932 | 0.70 | ALDH1A1 (0.34) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL5033931 | 0.70 | ALDH1A1 (0.34) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL27856491 | 0.69 | CA1 (0.32) | — | |
| SCHEMBL29020427 | 0.69 | ALDH1A1 (0.45) | ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL2994002 | 0.69 | CA1 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL26348120 | 0.68 | — | — | |
| SCHEMBL29783265 | 0.67 | TSHR (0.43) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713781-A1 | QUINAZOLINE DERIVATIVES | AstraZeneca AB (SE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005075439-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | WO | disclosed |