SCHEMBL6009475

SCHEMBL6009475

CC(=NNC=NN)c1cccc(NN2Cc3c(c(C)c(O)c4ccccc34)S2)c1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
GAA P10253 2/20 0.33
RAB9A P51151 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6074466 0.71 PTGS1 (0.39) MEN1GAARAB9AKMT2ANPC1
Hydrochloric Acid SCHEMBL6074390 0.71 PTGS1 (0.39) MEN1GAARAB9AKMT2ANPC1
SCHEMBL6741215 0.63 ALDH1A1 (0.57) MEN1GAARAB9AKMT2ANPC1
Hydrochloric Acid SCHEMBL6846976 0.62 ALDH1A1 (0.56) MEN1GAARAB9AKMT2ANPC1
SCHEMBL6746563 0.61 PARP1 (0.57) MEN1GAARAB9AKMT2ANPC1
SCHEMBL6074447 0.56 PLK4 (0.43) MEN1GAARAB9AKMT2ANPC1
SCHEMBL6074435 0.56 PLK4 (0.43) MEN1GAARAB9AKMT2ANPC1
Hydrochloric Acid SCHEMBL6074379 0.56 PLK4 (0.42) MEN1GAARAB9AKMT2ANPC1
Hydrochloric Acid SCHEMBL6074385 0.56 PLK4 (0.42) MEN1GAARAB9AKMT2ANPC1
Hydrochloric Acid SCHEMBL6009714 0.55 NPC1 (0.39) MEN1GAARAB9AKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1368029-A4 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS LLC (US) 2006-02-15 EP disclosed
EP-1368029-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS Farrington Pharmaceuticals, LLC (US) 2003-12-10 EP disclosed
WO-2002062301-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS, LLC (US) 2002-08-15 WO disclosed