SCHEMBL6009558

SCHEMBL6009558

COC(=O)c1cccc2[nH]c3cccc(C)c3c12

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 4/20 0.48
MET P08581 1/20 0.44
CREBBP Q92793 1/20 0.44
PKN1 Q16512 1/20 0.44
PKN2 Q16513 1/20 0.44
JAK2 O60674 1/20 0.44
LMNA P02545 1/20 0.43
TSHR P16473 1/20 0.43
PIM3 Q86V86 1/20 0.42
ALDH1A1 P00352 2/20 0.42
HSD17B10 Q99714 2/20 0.42
CFTR P13569 1/20 0.42
KMT2A Q03164 2/20 0.42
ATM Q13315 2/20 0.42
MEN1 O00255 1/20 0.42
ALOX5 P09917 1/20 0.41
KDM4E B2RXH2 2/20 0.41
RIPK1 Q13546 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6007667 0.92 NR4A2 (0.53) NR4A2METCREBBPPKN1PKN2
SCHEMBL6008342 0.84 TSHR (0.54) TSHRALDH1A1HSD17B10KMT2AMEN1
SCHEMBL6688990 0.83 ALDH1A1 (0.52) NR4A2METCREBBPPKN1PKN2
SCHEMBL31670359 0.81 NR4A2 (0.55) NR4A2CREBBPJAK2LMNATSHR
SCHEMBL2181558 0.81 NR4A2 (0.55) NR4A2CREBBPJAK2LMNATSHR
SCHEMBL30522265 0.81 NR4A2 (0.55) NR4A2CREBBPJAK2LMNATSHR
SCHEMBL28473965 0.80 NR4A2 (0.49) NR4A2LMNATSHRALDH1A1HSD17B10
SCHEMBL15987449 0.78 NR4A2 (0.48) NR4A2METCREBBPPKN1PKN2
SCHEMBL9937305 0.77 NR4A2 (0.70) NR4A2CREBBP
SCHEMBL29886596 0.77 NR4A2 (0.61) NR4A2CREBBPLMNATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060183022-A1 Electrochemical cell NEC TOKIN CORORATION (JP) 2006-08-17 US disclosed