Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009391 | 0.81 | SCN8A (0.49) | SCN8ACHRM2CA12CA1CA2 | |
| SCHEMBL4656040 | 0.81 | SCN8A (0.59) | SCN8ACHRM2EPHX2NR1H4SLC6A5 | |
| SCHEMBL6009935 | 0.79 | CHRM2 (0.66) | SCN8ACHRM2CA12CA1CA2 | |
| SCHEMBL29306669 | 0.79 | L3MBTL1 (0.55) | MMP1MMP2MMP9MMP14ADAM17 | |
| SCHEMBL10875607 | 0.78 | SCN8A (0.59) | SCN8ACHRM2EPHX2NR1H4SLC6A5 | |
| SCHEMBL9903315 | 0.77 | SCN8A (0.58) | SCN8ACHRM2EPHX2NR1H4CA12 | |
| SCHEMBL14048125 | 0.77 | SCN8A (0.61) | SCN8ACHRM2EPHX2NR1H4 | |
| SCHEMBL8348550 | 0.77 | SCN8A (0.55) | SCN8AEPHX2NR1H4HTR2C | |
| SCHEMBL355305 | 0.76 | CHRM2 (0.66) | SLC2A1CHRM2CA12CA1CA2 | |
| SCHEMBL27941504 | 0.76 | CHRM2 (0.66) | CHRM2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | APP, PSEN1, TTR | SCN8A 1893/4885SLC2A1 1363/4885CHRM2 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.