Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204256 | 0.85 | TAAR1 (0.41) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL14402510 | 0.83 | TAS1R3 (0.40) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL13849907 | 0.83 | TAS1R3 (0.40) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL14402859 | 0.80 | TAAR1 (0.37) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL5681973 | 0.80 | TAAR1 (0.43) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL15067498 | 0.80 | TAAR1 (0.43) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL28558103 | 0.80 | TAAR1 (0.43) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL4680286 | 0.79 | TAAR1 (0.48) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL27999583 | 0.78 | TAAR1 (0.52) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL4629058 | 0.78 | TAAR1 (0.50) | TAAR1CYP3A4CYP2D6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183800-A1 | Methods and fluorinated compositions for treating amyloid-related diseases | APP, PSEN1, TTR | TAAR1 1542/4885CYP3A4 1704/4885CYP2D6 2171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.