SCHEMBL6010037

SCHEMBL6010037

CN(C)[C@@H](CO)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6010020 1.00
SCHEMBL1132231 1.00
SCHEMBL19432853 0.79
SCHEMBL572461 0.79
SCHEMBL1432655 0.78 CA1 (0.30)
SCHEMBL1432542 0.78 CHRNB2 (0.35)
SCHEMBL10349045 0.77 TDP1 (0.37)
SCHEMBL27627024 0.77
SCHEMBL5886282 0.77 TDP1 (0.37)
SCHEMBL199040 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3319970-B1 PYRIDO-OXAZINONE DERIVATIVES AS TNAP INHIBITORS DAIICHI SANKYO CO LTD (JP) 2019-08-28 EP disclosed
US-10221195-B2 Pyridine compounds DAIICHI SANKYO COMPANY, LIMITED (JP) 2019-03-05 US disclosed
US-20180141960-A1 PYRIDINE COMPOUNDS DAIICHI SANKYO COMPANY, LIMITED (JP) 2018-05-24 US disclosed
US-9920068-B2 Pyridine compounds DAIICHI SANKYO COMPANY, LIMITED (JP) 2018-03-20 US disclosed
US-9879032-B2 Pyridine compounds DAIICHI SANKYO COMPANY, LIMITED (JP) 2018-01-30 US disclosed
US-20170240562-A1 PYRIDINE COMPOUNDS DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-08-24 US disclosed
US-20170210755-A1 PYRIDINE COMPOUNDS DAIICHI SANKYO COMPANY, LIMITED (JP) 2017-07-27 US disclosed
US-8772277-B2 Nitrogen-containing heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-07-08 US disclosed
US-20130072467-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED 2013-03-21 US disclosed
WO-2013018929-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-02-07 WO disclosed
EP-1713781-A1 QUINAZOLINE DERIVATIVES AstraZeneca AB (SE) 2006-10-25 EP disclosed
WO-2005075439-A1 QUINAZOLINE DERIVATIVES ASTRAZENECA AB (SE) 2005-08-18 WO disclosed
US-5089491-A Active against both gram-negative and gram-positive bacteria EISAI CO., LTD. (JP) 1992-02-18 US disclosed
EP-0264091-B1 3-PROPENYLCEPHEM DERIVATIVE, PREPARATION THEREOF, CHEMICAL INTERMEDIATES THEREIN, PHARMACEUTICAL COMPOSITION AND USE Eisai Co., Ltd. (JP) 1992-02-05 EP disclosed
US-5066812-A Chemical intermediates for bactericides EISAI CO., LTD. (JP) 1991-11-19 US disclosed
US-5006649-A Bactericides EISAI, CO. (JP) 1991-04-09 US disclosed
US-4921850-A GRAMNEGATIVE AND GRAMPOSITIVE BACTERICIDE EISAI CO., LTD. (JP) 1990-05-01 US disclosed