SCHEMBL6010191

SCHEMBL6010191

CCCCCCOC(=O)/C(C#N)=C/c1ccc(OC)cc1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.59
DNM1 Q05193 2/20 0.57
LMNA P02545 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
KDM4E B2RXH2 7/20 0.54
HPGD P15428 4/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
GAA P10253 1/20 0.54
MAPT P10636 3/20 0.53
RAB9A P51151 1/20 0.53
PKM P14618 1/20 0.52
HTT P42858 1/20 0.52
RECQL P46063 1/20 0.51
SAE1 Q9UBE0 1/20 0.51
UBA2 Q9UBT2 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6010195 1.00 ALDH1A1 (0.59) ALDH1A1DNM1LMNAMEN1KMT2A
SCHEMBL10992547 1.00 ALDH1A1 (0.59) ALDH1A1DNM1LMNAMEN1KMT2A
SCHEMBL6009691 1.00 ALDH1A1 (0.59) ALDH1A1DNM1LMNAMEN1KMT2A
SCHEMBL6010192 1.00 ALDH1A1 (0.59) ALDH1A1DNM1LMNAMEN1KMT2A
SCHEMBL5838471 1.00 ALDH1A1 (0.59) ALDH1A1DNM1LMNAMEN1KMT2A
SCHEMBL6009690 1.00 ALDH1A1 (0.59) ALDH1A1DNM1LMNAMEN1KMT2A
SCHEMBL6747451 1.00 ALDH1A1 (0.59) ALDH1A1DNM1LMNAMEN1KMT2A
SCHEMBL10992550 1.00 ALDH1A1 (0.59) ALDH1A1DNM1LMNAMEN1KMT2A
SCHEMBL7866447 0.90 ALDH1A1 (0.64) ALDH1A1DNM1LMNAMEN1KMT2A
SCHEMBL7866449 0.90 ALDH1A1 (0.64) ALDH1A1DNM1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed
US-4284621-A SUNSCREEN FOR SKIN BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US claimed
EP-0005182-B1 COMPOSITION AGAINST THE ACTION OF LIGHT BAYER AG (DE) 1981-07-29 EP claimed
US-11389386-B2 Photochemically stable, non-leaching, bridged polysilsesquioxane based sunscreens ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2022-07-19 US disclosed
US-20190038537-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING, BRIDGED POLYSILSESQUIOXANE BASED SUNSCREENS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2019-02-07 US disclosed
EP-1353628-B1 HAIR PROTECTION COMPOSITIONS DSM IP ASSETS BV (NL) 2006-11-02 EP disclosed
WO-2004062635-A1 COMPOSITIONS FOR SKIN LIGHTENING COMPRISING BIS-PANTOYL-CYSTAMINE DSM IP ASSETS B.V. (NL) 2004-07-29 WO disclosed
WO-2004062633-A1 HAIR CARE COMPOSITIONS COMPRISING BIS - PANTOYL - CYSTAMINE OR A DERIVATIVE THEREOF DSM IP ASSETS B.V. (NL) 2004-07-29 WO disclosed
WO-2004045567-A1 USE OF ASCORBIC ACID DERIVATIVES IN HAIR CARE PRODUCTS DSM IP ASSETS B.V. (NL) 2004-06-03 WO disclosed
EP-1353628-A2 HAIR PROTECTION COMPOSITIONS Roche Vitamins AG (CH) 2003-10-22 EP disclosed
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US disclosed
WO-2002055029-A2 HAIR PROTECTION COMPOSITIONS ROCHE VITAMINS AG (CH) 2002-07-18 WO disclosed
US-4284621-A SUNSCREEN FOR SKIN BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11389386-B2 Photochemically stable, non-leaching, bridged polysilsesquioxane based sunscreens SQLE, STS, RAD52 ALDH1A1 1246/4885DNM1 4791/4885LMNA 630/4885
US-20190038537-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING, BRIDGED POLYSILSESQUIOXANE BASED SUNSCREENS SQLE, STS, RAD52 ALDH1A1 1422/4885DNM1 4797/4885LMNA 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.