⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL932027 | 0.72 | — | — | |
| SCHEMBL27674320 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL933127 | 0.71 | — | — | |
| SCHEMBL933257 | 0.70 | — | — | |
| SCHEMBL28858341 | 0.69 | — | — | |
| SCHEMBL4436164 | 0.69 | — | — | |
| SCHEMBL18281302 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL27863821 | 0.67 | — | — | |
| Formaldehyde SCHEMBL27690920 | 0.67 | — | — | |
| Bicarbonate SCHEMBL28210330 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689751-A1 | 5,7-DIAMINOPYRAZOLO¬4,3-D|PYRIMIDINES WITH PDE-5 INHIBITING ACTIVITY | Pfizer Limited (GB) | 2006-08-16 | — | — | EP | claimed |
| WO-2005049616-A1 | 5,7-DIAMINOPYRAZOLO [4,3-d] PYRIMIDINES WITH PDE-5 INHIBITING ACTIVITY | PFIZER LIMITED (GB) | 2005-06-02 | — | — | WO | claimed |