Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.57 |
| ▸ | FNTB | P49356 | 7/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171779 | 0.84 | FNTA (0.55) | FNTAFNTBHSD17B10 | |
| SCHEMBL7209358 | 0.83 | HSD17B10 (0.72) | FNTAFNTBHSD17B10KMT2APGR | |
| SCHEMBL29372174 | 0.83 | HSD17B10 (0.72) | FNTAFNTBHSD17B10KMT2APGR | |
| SCHEMBL8171501 | 0.82 | FNTA (0.53) | FNTAFNTBHSD17B10MEN1KMT2A | |
| SCHEMBL11955322 | 0.80 | FNTA (0.60) | FNTAFNTBHSD17B10 | |
| SCHEMBL30419724 | 0.79 | FNTA (0.56) | FNTAFNTBHSD17B10KMT2A | |
| SCHEMBL1538260 | 0.79 | FNTA (0.56) | FNTAFNTBHSD17B10KMT2A | |
| SCHEMBL24095575 | 0.79 | HSD17B10 (0.69) | FNTAFNTBHSD17B10MEN1KMT2A | |
| SCHEMBL1644048 | 0.79 | FNTA (0.48) | FNTAFNTBHSD17B10 | |
| SCHEMBL27251471 | 0.78 | FNTA (0.66) | FNTAFNTBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7067531-B2 | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinolinone derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-06-27 | — | — | US | disclosed |
| US-20030199547-A1 | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinolinone derivatives | JANSSEN-CILAG S.A. (FR) | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199547-A1 | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinolinone derivatives | FNTA, FNTB, RCE1 | FNTA 1/4885FNTB 2/4885HSD17B10 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.