Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14783054 | 0.98 | MAOB (0.56) | MAOBFBP1ALDH1A1HDAC2LMNA | |
| Hydrochloric Acid SCHEMBL14783053 | 0.98 | MAOB (0.56) | MAOBFBP1ALDH1A1HDAC2LMNA | |
| SCHEMBL8454093 | 0.84 | MAOB (0.58) | MAOBFBP1ALDH1A1HDAC2LMNA | |
| SCHEMBL9457910 | 0.81 | MAOB (0.59) | MAOBFBP1ALDH1A1HDAC2LMNA | |
| SCHEMBL9457904 | 0.81 | MAOB (0.59) | MAOBFBP1ALDH1A1HDAC2LMNA | |
| SCHEMBL29260529 | 0.81 | MAOB (0.56) | MAOBFBP1ALDH1A1HDAC2LMNA | |
| SCHEMBL29260527 | 0.81 | MAOB (0.56) | MAOBFBP1ALDH1A1HDAC2LMNA | |
| SCHEMBL24358835 | 0.79 | MAOB (0.54) | MAOBFBP1ALDH1A1HDAC2LMNA | |
| SCHEMBL8450086 | 0.79 | MAOB (0.53) | MAOBFBP1ALDH1A1HDAC2LMNA | |
| SCHEMBL15964288 | 0.79 | MAOB (0.64) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055096-A1 | DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIVERSITY OF LJUBLJANA (SI) | 2018-03-29 | — | — | WO | disclosed |
| EP-1785415-B1 | PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |