Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.59 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457910 | 1.00 | MAOB (0.59) | MAOBFBP1HDAC2ALDH1A1LMNA | |
| SCHEMBL10417335 | 0.89 | MAOB (0.49) | MAOBFBP1HDAC2ALDH1A1LMNA | |
| SCHEMBL8454093 | 0.83 | MAOB (0.58) | MAOBFBP1HDAC2ALDH1A1LMNA | |
| SCHEMBL6011001 | 0.81 | MAOB (0.57) | MAOBFBP1HDAC2ALDH1A1LMNA | |
| SCHEMBL8450086 | 0.81 | MAOB (0.53) | MAOBFBP1HDAC2ALDH1A1LMNA | |
| SCHEMBL15964288 | 0.81 | MAOB (0.64) | MAOBMAOA | |
| SCHEMBL8450091 | 0.81 | MAOB (0.53) | MAOBFBP1HDAC2ALDH1A1LMNA | |
| SCHEMBL29260527 | 0.80 | MAOB (0.56) | MAOBFBP1HDAC2ALDH1A1LMNA | |
| SCHEMBL29260529 | 0.80 | MAOB (0.56) | MAOBFBP1HDAC2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL14783053 | 0.80 | MAOB (0.56) | MAOBFBP1HDAC2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238602-A | Electrooptical cells | HOFFMANN LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |
| US-5013478-A | Electromagnetic radiation resistance; miscibility; dielectrics; rotation and guest/host cells | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |
| US-4980486-A | Phenyl isothiocyanates | HOFFMANN-LA ROCHE INC. (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0168683-B1 | LIQUID CRYSTALS WITH ALKENYL OR ALKENYLOXY GROUPS | F. HOFFMANN-LA ROCHE AG (CH) | 1990-11-28 | — | — | EP | disclosed |
| US-4915480-A | Liquid crystalline compounds and mixtures | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | disclosed |
| EP-0167912-B1 | LIQUID CRYSTAL MIXTURES CONTAINING COMPOUNDS WITH A 4-ALKENYL OR 2Z-ALKENYL LATERAL CHAIN | F. HOFFMANN-LA ROCHE AG (CH) | 1990-01-03 | — | — | EP | disclosed |
| EP-0169327-B1 | PHENYLISOTHIOCYANATES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-01-13 | — | — | EP | disclosed |
| US-4709030-A | 4-ALKENYL OR 2Z-ALKENYL POLYPHENYL COMPOUNDS; ELECTRO-OPTICS | HOFFMANN-LA ROCHE INC. (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0122389-B1 | LIQUID CRYSTAL COMPONENTS HAVING AN ALKENYL CHAIN | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-08-05 | — | — | EP | disclosed |
| US-4676604-A | RADIATION RESISTANCE; MISCIBILITY; ROTATION ELECTROPTICAL CELLS | HOFFMANN-LA ROCHE INC. (US) | 1987-06-30 | — | — | US | disclosed |
| US-4621901-A | ELECTROOPTICS | HOFFMANN-LA ROCHE INC. (US) | 1986-11-11 | — | — | US | disclosed |
| EP-0172360-A2 | Cyclohexanecarbonitriles and their use as components for liquid crystals | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-02-26 | — | — | EP | disclosed |
| EP-0169327-A2 | Phenylisothiocyanates | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-01-29 | — | — | EP | disclosed |
| EP-0168683-A2 | Liquid crystals with alkenyl or alkenyloxy groups | F. HOFFMANN-LA ROCHE AG (CH) | 1986-01-22 | — | — | EP | disclosed |
| US-4565425-A | Liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0167912-A2 | Liquid crystal mixtures containing compounds with a 4-alkenyl or 2Z-alkenyl lateral chain | F. HOFFMANN-LA ROCHE AG (CH) | 1986-01-15 | — | — | EP | disclosed |
| EP-0122389-A2 | Liquid crystal components having an alkenyl chain | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-10-24 | — | — | EP | disclosed |