Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476005 | 0.79 | HTR2C (0.47) | SLC18A3SIGMAR1KHKHTR2CKDM1A | |
| SCHEMBL1476002 | 0.79 | HTR2C (0.47) | SLC18A3SIGMAR1KHKHTR2CKDM1A | |
| SCHEMBL1477279 | 0.79 | MAOA (0.54) | MAOAMAOBKDM1ASLC6A2SLC6A4 | |
| SCHEMBL2719317 | 0.79 | DYRK2 (0.40) | SLC18A3SIGMAR1MAOAMAOBCHRM1 | |
| SCHEMBL2719321 | 0.79 | DYRK2 (0.40) | SLC18A3SIGMAR1MAOAMAOBCHRM1 | |
| SCHEMBL13794937 | 0.79 | HTR2C (0.47) | SLC18A3SIGMAR1KHKHTR2CKDM1A | |
| SCHEMBL1477276 | 0.79 | MAOA (0.54) | MAOAMAOBKDM1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL1476297 | 0.78 | MAOA (0.52) | MAOAMAOBKDM1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL1476298 | 0.78 | MAOA (0.52) | MAOAMAOBKDM1ASLC6A2SLC6A4 | |
| SCHEMBL27587831 | 0.77 | HRH1 (0.47) | SLC18A3SIGMAR1HRH1CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1785415-B1 | PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |
| EP-1785415-A1 | PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Astellas Pharma Inc. (JP) | 2007-05-16 | — | — | EP | disclosed |