Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 5/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA3 | P07451 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069269 | 0.81 | MAOB (0.51) | MAOBALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6011041 | 0.81 | MAOB (0.51) | CYP2D6CA1MAOBALDH1A1MAPT | |
| SCHEMBL30683539 | 0.81 | MAOB (0.51) | CYP2D6CA1MAOBALDH1A1MAPT | |
| SCHEMBL5213208 | 0.81 | MAOB (0.51) | HSD11B1APPMAOBMAOASLC6A2 | |
| SCHEMBL6011685 | 0.81 | MAOB (0.51) | CYP2D6MAOBKDM4EALDH1A1CYP1A2 | |
| SCHEMBL20015683 | 0.81 | KDM1A (0.51) | MAOBALDH1A1LMNAKDM1AMAOA | |
| SCHEMBL27140897 | 0.81 | KDM1A (0.51) | MAOBALDH1A1LMNAKDM1AMAOA | |
| SCHEMBL818902 | 0.81 | KDM1A (0.51) | MAOBALDH1A1LMNAKDM1AMAOA | |
| SCHEMBL20015402 | 0.80 | MAOB (0.52) | MAOBSMN1; SMN2HPGDKMT2AKDM1A | |
| Hydrochloric Acid SCHEMBL27134589 | 0.80 | MAOB (0.50) | CYP2D6CA1MAOBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1785415-B1 | PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |