Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KHK | P50053 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20015683 | 1.00 | KDM1A (0.51) | KDM1AMAOAMAOBKHKSLC18A3 | |
| SCHEMBL27140897 | 1.00 | KDM1A (0.51) | KDM1AMAOAMAOBKHKSLC18A3 | |
| Hydrochloric Acid SCHEMBL27154699 | 0.98 | KDM1A (0.50) | KDM1AMAOAMAOBKHKSLC18A3 | |
| Hydrochloric Acid SCHEMBL7469122 | 0.98 | KDM1A (0.50) | KDM1AMAOAMAOBKHKSLC18A3 | |
| Hydrochloric Acid SCHEMBL7469111 | 0.98 | KDM1A (0.50) | KDM1AMAOAMAOBKHKSLC18A3 | |
| SCHEMBL6011015 | 0.89 | KHK (0.45) | KDM1AMAOAMAOBKHKSLC18A3 | |
| SCHEMBL817532 | 0.89 | KDM1A (0.46) | KDM1AMAOAMAOBKHKALDH1A1 | |
| SCHEMBL6011007 | 0.86 | HTR1A (0.46) | KDM1AKHKALDH1A1LMNA | |
| SCHEMBL9539801 | 0.85 | MAOA (0.56) | KDM1AMAOAMAOBALDH1A1LMNA | |
| SCHEMBL1610007 | 0.85 | MAOA (0.56) | KDM1AMAOAMAOBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102105471-B | Novel compounds useful for the treatment of degenerative and inflammatory diseases | GALAPAGOS N.V. (BE) | 2014-10-15 | — | — | CN | disclosed |
| CN-102282132-A | Inhibitors of diacylglycerol acyltransferase | — | 2011-12-14 | — | — | CN | disclosed |
| US-20110275756-A1 | CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20110245398-A1 | METHOD FOR PRODUCING CONJUGATED DIENE POLYMER COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-10-06 | — | — | US | disclosed |
| CN-101160287-B | Pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate ester derivative | ASTELLAS PHARMA INC | 2011-08-03 | — | — | CN | disclosed |
| CN-102105471-A | Novel compounds useful for the treatment of degenerative and inflammatory diseases | GALAPAGOS NV | 2011-06-22 | — | — | CN | disclosed |
| CN-100413860-C | piperidine derivatives as NMDA receptor antagonists | HUNGARY GIREL GYOGYSZERGYAR (HU) | 2008-08-27 | — | — | CN | disclosed |
| CN-101160287-A | Pyridyl non-aromatic nitrogenated heterocyclic-1-carboxylate ester derivative | ASTELLAS PHARMA INC (JP) | 2008-04-09 | — | — | CN | disclosed |
| CN-1556805-A | piperidine derivatives as NMDA receptor antagonists | ������ҩ������˾ | 2004-12-22 | — | — | CN | disclosed |
| CN-1076022-C | Cyclic ether compounds as sodium channel modulators | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | CN | disclosed |
| CN-1223652-A | Cyclic ether compounds as sodium channel modulators | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-21 | — | — | CN | disclosed |