Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | WNT3 | P56703 | 1/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14261804 | 0.88 | NPC1 (0.46) | TSHRALOX15HSD17B10NAMPTWNT3 | |
| SCHEMBL6011965 | 0.88 | MAOB (0.43) | TSHRALOX15HSD17B10NAMPTWNT3 | |
| SCHEMBL10069075 | 0.87 | MAPT (0.47) | TSHRALOX15HSD17B10NAMPTKDM4E | |
| SCHEMBL14261824 | 0.87 | HTT (0.47) | TSHRALOX15HSD17B10NAMPTWNT3 | |
| SCHEMBL6009399 | 0.87 | MAOA (0.54) | TSHRALOX15HSD17B10NAMPTWNT3 | |
| SCHEMBL6012016 | 0.87 | KMT2A (0.46) | TSHRALOX15HSD17B10NAMPTKMT2A | |
| SCHEMBL14261820 | 0.87 | MAOA (0.54) | TSHRALOX15HSD17B10NAMPTWNT3 | |
| SCHEMBL14261811 | 0.87 | HTT (0.47) | TSHRALOX15HSD17B10NAMPTWNT3 | |
| SCHEMBL10069273 | 0.87 | TSHR (0.44) | TSHRALOX15HSD17B10NAMPTWNT3 | |
| SCHEMBL6011003 | 0.87 | TSHR (0.44) | TSHRALOX15HSD17B10NAMPTWNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1785415-B1 | PIPERIDINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |